Physical Biochemistry Facility

The Physical Biochemistry Facility (PBF) provides state-of-the-art resources for biophysical studies of macromolecules. The facility was established as a collaborative effort of Drs. Michael Blaber, Donald Caspar, and Timothy Logan, the Institute of Molecular Biophysics, Department of Chemistry and Biochemistry, and Department of Biological Science at the Florida State University.

The People

In conjunction with the Macromolecular X-ray Facility and the NMR facilities at the National High Magnetic Field Laboratory, the PBF provides researchers at FSU with means to study the biophysical properties of biomolecules. In addition to the instrumental resources, the facility provides consultation, training by the Director Dr. Peter Randolph and assistance with instrument operation, experimental design and data analysis to the scientific community of the Florida State University and Florida A&M University.

Resources

Special emphasis is placed on providing resources, training, and guidance to graduate and undergraduate students. The PBF offers access to a broad range of instrumentation that is usually not available in an individual laboratory. Consequently, students have the opportunity to familiarize themselves with different biophysical techniques and evaluate their suitability to a particular study. The PBF also provides a forum for communication and exchange of ideas among students in their research efforts.

Physical Biochemistry Facility Fee Structure

Starting from July 1, 2010 PBF has instituted a user-fee to defray part of the cost of the running the Facility. Click PBF User Fees  to find more information. All users are required to bring filled and signed Inter-Departmental Requistion Form BEFORE they can bring their work at the Facility.

PBF Notes

Facility Director
Peter Randolph, Ph.D.

Office: 850-644-1626
Lab Phone: 850-645-4967
prandolph@fsu.edu

 

A Core Facility of the Structural Biology Program, established 1993.
Housed in Rm KLB 311-317
Kasha Laboratory Building
91 Chieftan Way
Florida State University
Tallahassee, FL 32306-4380

PBF Workshop
In early August, PBF runs a Core Facility Practical Training Course (Boot Camp) for all new graduate students. More information  is available here.

Resources
Analytical Ultracentrifuge
Circular Dichroism
Isothermal Titration Calorimetry
Dynamic Light Scattering
Stopped Flow Kinetics
Differential Scanning Calorimetry
Fluorescence spectrofluorimeter
UV/Vis Spectrophotometer
Quench- Flow System
Other small equipment:
   Nanodrop UV/Vis and Fluorescence
Refractometer
Sonicator