• Institute of Molecular Biophysics
  • Ph.D. in Computational Physics
  • phone: (850) 644-4104
  • zhuangdvm@gmail.com


  • Department of Physics, Fudan University, Shanghai, China

Summary of The job duties:

  • Developing methods, algorithms and software for electron 2D crystals and electron tomography.
  • Apply single particle approach to investigate integrin-alpha actinin binding protein complex, talin crystals.
  • Extend normal mode flexible fitting approach to investigate the conformational changes of myosin II, and insect flight muscle.


  • Melanie D. Ohi, Anna Feoktistova, Liping Ren, Calvin Yip, Yifan Cheng, Jun-Song Chen, Joseph S. Wall, Zhong Huang , Pawel A. Penczek, Kathleen L. Gould, and Thomas Walz. Structural organization of the Anaphase-Promoting Complex bound to the Mitotic Activator Slp. 2007 Molecular Cell, 28: 871-885.
  • Michael Hohn, Grant Tang, Grant Goodyear, P. R. Baldwin, Zhong Huang, Pawel A. Penczek, Chao Yang, Robert M. Glaeser, Paul D. Adams, and Steven J. Ludtke. SPARX, a new environment for cryo-EM image processing. 2006, J. Strut. Biology, 157(1): 47-55.
  • Lee. Pullan, Srinivas Mullapudi, Zhong Huang, Phillip R. Baldwin, Christopher Chin, Wei Sun, Suan Tshjimoto, Steven J. Kolodziej, James K. Stoops, James C. Lee, M. Neal Waxham, Andrew J. Bean, and Pawel Penczek. The endosome-associated protein Hrs is hexameric and controls cargo sorting as a master molecule. 2006, Structure,14: 661-671.
  • Zhong Huang and Pawel Penczek. Application of template matching technique to particle detection in electron micrographs. 2004, J. Struct. Biology, 145: 29-40.
  • Zhong Huang, Philip R. Baldwin, Srinivas Mullapudi, and Pawel A. Penczek. Automated determination of parameters describing power spectra of micrograph images in electron microscopy. 2003, J. Struct. Biology, 144: 79-94.
  • Yu Fu, Zhong Huang, Ling Ye, and Xun Wang. The strong correlation of the 4f electrons of erbium atoms in silicon. 2003, J. Phys. Condens. Matt. 15: 1437-1444.
  • Dengming Ming, Yifei Kong, Maxime Lambert, Zhong Huang, and Jianpeng Ma. How to describe the movement of Protein without amino acids sequence and coordinates. 2002, P. N. A. S, 99, No.13: 8620-8625.

List of selected links about my software & methodology development:

  1. http://www.wadsworth.org/spider_doc/spider/docs/man/tfed.html
  2. http://www.wadsworth.org/spider_doc/spider/docs/man/pdbcg3.html
  3. http://www.wadsworth.org/spider_doc/spider/docs/man/pdbif.html

Selected items of contributions to SPARX:

  1. http://www.macro-em.org/sparxwiki/flcc

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