Peng, Yu

Yu Peng, Ph.D.

Postdoctoral Researcher
Dr. Hong Li’s Group
Office – KLB 206
Lab – KLB 210
Email – ypeng@fsu.edu


RESEARCH INTERESTS
Bacteria and archaea employ CRISPR systems to fight against invading genetic materials , such as plasmids and phages.  I’m currently engaged in solving structures of the functional protein complex of CRISPR systems using X-ray crystallographic method.

EDUCATION
2005-2010 –Ph.D. – Shanghai Institute of Materia Medica, CAS – Medicinal Chemistry
2002-2005 –M.S.– Wuhan University  – Biology
1997-2002  –B.S. – Wuhan University – Medicine

PUBLICATIONS

  • Sun L, Wu X, Peng Y, Goh JY, Liou YC, Lin D, Zhao Y, “Solution structural analysis of the single-domain parvulin TbPin1.PLoS One. 7(8):e43017 (2012)
  • Fu C, Peng Y, Liao X, Guo C, Lin D. “(1)H, (13)C, (15)N backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form.Biomol NMR Assign. (2012)
  • Peng Y, Zhang X, Liu J, Liu Q, Guo C, Zhang Y, Lin D, “Solution structure of the protein lipocalin 12 from rat epididymis.”  Proteins. 79(7):2316-20 (2011)
  • Peng Y, Liu J, Liu Q, Yao Y, Guo C, Zhang Y, Lin D, “Conformational and biochemical characterization of a rat epididymis-specific lipocalin 12 expressed in Escherichia coli.”  Biochim Biophys Acta. 1804(11):2102-10. (2010)
  • Wen Y, Li J, Xiong M, Peng Y, Yao W, Hong J, Lin D, “Solution structure and dynamics of the I214V mutant of the rabbit prion protein.” PLoS One. Oct 7;5(10):e13273. ( 2010)
  • Song AX, Zhou CJ, Peng Y, Gao XC, Zhou ZR, Fu QS, Hong J, Lin DH, Hu HY, “Structural transformation of the tandem ubiquitin-interacting motifs in ataxin-3 and their cooperative interactions with ubiquitin chains.” PLoS One. 7;5(10):e13202. (2010)
  • Yi C, Peng Y, Guo C, Lin D, “1H, 13C, 15N backbone and side-chain resonance assignments of the human Raf-1 kinase inhibitor protein.” Biomol NMR Assign. 5(1):63-6, (2010)
  • Wen Y, Li J, Yao W, Xiong M, Hong J, Peng Y, Xiao G, Lin D, “Unique structural characteristics of the rabbit prion protein.” J Biol Chem. 8;285(41):31682-93. (2010)
  • Yao W, Peng Y, Lin D, “The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity,” Biochem Biophys Res Commun. 28;396(2):323-8.(2010)
  • Yao W, Peng Y, Chen Q, Lin D, “1H, 13C, 15N backbone and side-chain resonance assignments of the Bright/ARID domain from the human histone demethylase JARID1B.” Biomol NMR Assign. 3(1):85-7.(2009)
  • Hussain S, Pan J, Xu J, Yang Y, Chen Y, Peng Y, Wu Y, Li Z, Zhu Y, Tien P, Guo D, “ Identification and characterization of severe acute respiratory syndrome coronavirus subgenomic RNAs.” Adv Exp Med Biol. 581:85-8. (2006)
  • Peng Y, Li S, Li Z, Wang J, Tien P, Guo D, “Interaction between Nucleocapsid Protein and the Leader Sequence of SARS-CoV RNA.” Virologica SINICA  20(5) (2005)
  • Li Z, Xiong Y, Peng Y, Pan J, Chen Y, Wu X, Hussain S, Tien P, Guo D. “Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis.” FEBS Lett.  6;579(14):3100-6. (2005)
  • Hussain S, Pan J, Chen Y, Yang Y, Xu J, Peng Y, Wu Y, Li Z, Zhu Y, Tien P, Guo D, “Identification of novel subgenomic RNAs and noncanonical transcription initiation signals of severe acute respiratory syndrome coronavirus.” J Virol. 79(9):5288-95. (2005)
  • Li S, Zhu J, Peng Y, Cui S, Wang C, Gao GF, Tien P, “Characterization of BIV Env core: implication for mechanism of BIV-mediated cell fusion.” Biochem Biophys Res Commun. 8;329(2):603-9.  (2005)

PRESENTATIONS

  • The Beijing Conference and Exhibition on Instrumental Analysis, Oct 15, 2011
    “Solution Structure of Rat Lipocalin 12 Protein And Its Interactions With Small-Molecule Ligands”
  • 5th Shanghai Structural Biology Network Meeting, May 15, 2010
    “Studies on Solution Structure of Rat Lipocalin 12 Protein and Interactions with Small-Molecule Ligands”