X-Ray Crystallography Facility

Following COVID-19 shutdown, XRF is now in Phase 4 of Ramp-up Operations.  Consult the XRF COVID-19 Ramp-up Document for more details.

As one of the FSU-wide Core Facilities, the multi-user macromolecular x-ray crystallography facility (XRF) at the Kasha Laboratory Building (KLB) in the Institute of Molecular Biophysics (IMB) provides training, expertise, and assistance for crystallizing and determining the three-dimensional structures of biological macromolecules and their complexes.  It is available to all the members of Structural Biology Program and others at FSU. XRF is located on the East side of the fourth floor of KLB (see the floor plan). More facility information is available at X-Ray Facility page.

Instruments & Accessories

XRF has Rigaku RU-H2R & RU-H3R x-ray generators, Osmic confocal mirror systems,  Rigaku R-Axis IV++ IP detector and Mar CCD165 detector. It has Oxford CryoStream cryo coolers, American Magnetics auto-refill system stereo-zoom microscopes, crystallization chambers maintained at variety of temperatures, and data processing hardware and software. It has  an Art Robbins Instruments Crystal Gryphon crystallization robot, Formulatrix Rock Imager 1 and Formulator 16, Rumed Crystal Incubator, and  IMB designed and home built simple robotic imager. The Facility has  a ThorLabs DCC1645C digital camera for the Leica S8 APO microscope. More Info >>>

Synchrotron Beam Access

The Facility Director also coordinates both remote and mail-in synchrotron x-ray diffraction data collection work using FSU’s membership in SER-CAT in Advanced Photon Source Beamline 22 and NSLS-II Beamline AMX-17ID-1 . More Info >>>

XRF Fee Structure

Starting from July 01, 2010 XRF charges  a user-fee to defray part of the cost of running the Facility. Please see XRF Fee Structure for more information about fees. Updated user fees go into effect Jul 01, 2019.

XRF Boot Camp

Every August before the start of the Fall semester, XRF runs a Boot Camp for new the graduate students. The three week Boot Camp is part of the Core Facilities Workshop. Please see XRF Boot Camp for this year’s schedule and syllabus. In 2020, due to COVID-19 XRF Bootcamp is deferred to a later date.

Updated:  August 24, 2020.