Analytical Ultracentrifuge

AUC Schematic Cartoon

“The analytical ultracentrifuge is still the most versatile, rigorous and accurate means for determining the molecular weight and the hydrodynamic and thermodynamic properties of a protein or other macromolecule. No other technique is capable of providing the same range of information with a comparable level of precision and accuracy. The reason for this is that the method of sedimentation analysis is firmly based in thermodynamics. All terms in the equations describing sedimentation behavior are experimentally determinable.”  More

Physical Biochemistry Facility